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Pharmaceutical Industry Decanter Centrifuge OEM

As a satisfactory enterprise in the field of centrifugal separation in China, Huading's decanter centrifuge has demonstrated strong technical adaptability in the pharmaceutical industry (including Chinese medicine extraction, biopharmaceuticals, chemical synthesis and other fields).
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Pharmaceutical Industry Decanter Centrifuge Manufacturers

In view of the particularity of the pharmaceutical industry (such as high added value of materials, strict process hygiene requirements, and high separation accuracy), Huading has achieved full-scene coverage from laboratory to industrial production through customized design and pharmaceutical-grade standard certification, and has solved key process problems such as alcohol precipitation of Chinese medicine, clarification of medicinal liquid, and dehydration of medicinal residues.

Technical features of decanter centrifuges for the pharmaceutical industry

Pharmaceutical-grade materials and structural design


  • Material selection

    Core components such as drums and spiral blades are made of 316L stainless steel or titanium alloy, which meets GMP standards, is corrosion-resistant and avoids metal ion contamination (such as the sensitivity of Chinese medicine extracts to iron ions).

  • Sanitary polishing

    Inner surface Ra≤0.4μm, reduces material residues, and meets CIP/SIP (online cleaning/sterilization) requirements.

  • Explosion-proof design

    For organic solvent environments (such as alcohol precipitation process), flameproof motors and fully enclosed structures are used, which comply with ATEX explosion-proof certification to ensure safety in flammable and explosive environments.

 

Precise separation and process adaptability


  • Optimization of separation factors

    For micron-sized particles in liquid medicine (such as suspended matter in traditional Chinese medicine with a particle size of 0.005-3mm), the separation factor reaches 3136-3567G, ensuring high-precision solid-liquid separation.

  • Adjustable parameter system

    Through variable frequency speed regulation (0-4500 RPM stepless adjustment) and differential speed control (0-45 RPM differential speed range), it can flexibly cope with liquid medicines of different viscosities (such as concentrated liquid medicines with a viscosity of up to 5000 mPa·s).

  • Three-phase separation capability

    Some models support liquid-liquid-solid three-phase synchronous separation (such as ethanol-liquid medicine-drug residue separation in traditional Chinese medicine alcohol precipitation), and the thickness of the liquid ring layer can be adjusted in real time through the adjustment ring.

 

Convenience of cleaning and maintenance


  • Multi-stage cleaning system

    Equipped with high-pressure nozzles (pressure ≥50 bar) and multi-channel CIP pipelines, it can remove the accumulated materials (such as sticky drug residues) inside the spiral, and the cleaning efficiency is increased by 60%.

  • Modular design

    The spiral conveyor adopts a quick-release structure for easy maintenance and replacement; the seals are made of food-grade silicone or PTFE to avoid cross contamination.

 

Core application scenarios and cases in the pharmaceutical industry

Traditional Chinese medicine alcohol precipitation process


  • Process requirements

    Separation of ethanol-liquid-drug residue three-phase mixture, requiring to avoid solvent volatilization and explosion risks.

  • Solution

    Use the explosion-proof LW450B centrifuge, and achieve a drug residue moisture content of ≤65% and an ethanol recovery rate of ≥95% through the "saddle-shaped" slag outlet design.

  • Case

    After using LW450B, a Chinese medicine injection company saved 1.2 million yuan in ethanol costs and increased separation efficiency by 40%.

Biopharmaceutical fermentation broth treatment


  • Process requirements

    Separation of mycelium and fermentation broth, is required to avoid cell rupture affecting active ingredients.

  • Solution

    LW350G adopts low shear spiral design, with differential speed controlled at 5-10 RPM, ensuring mycelium integrity rate ≥ 98%

 

Dehydration and resource utilization of drug residues


  • Process requirements

    Reduce the moisture content of drug residues from 80% to below 50% to facilitate subsequent incineration or composting.

  • Solution

    LW520X achieves continuous slag discharge through high-torque planetary gears (12000N·m), with a processing capacity of 15m³/h and energy consumption reduced by 35% compared with traditional filter presses

Operation and maintenance points

Check the wear of spiral blades every 500 hours, and perform dynamic balancing correction when necessary (allow residual imbalance ≤5g·mm/kg)

Use purified water + 1% nitric acid solution for cleaning to ensure no cleaning agent residue

Product Category:
Pharmaceutical Industry Decanter Centrifuge
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Company
Yixing Huading Machinery Co.,Ltd.
Yixing Huading Machinery Co.,Ltd. (Huading Separator) was established in 1954. It is reputable China Pharmaceutical Industry Decanter Centrifuge Manufacturers and OEM Pharmaceutical Industry Decanter Centrifuge Factory of specialized products and engineering solutions in China, relying on its own key technologies for clarification, purification, and concentration.
The equipment (disc centrifuge, decanter centrifuge), systems, and services provided by Huading are specifically designed to help customers improve the performance of optimized processes. The solutions provided by Huading can help customers solve separation and filtration problems in the production process.
Huading's disc centrifuges and decanter centrifuges serve the industries of biomedicine, beverages, plant extraction, dairy products, the oil industry, chemical energy, water treatment, and other industries. The capacity of disc centrifuges and decanter centrifuges ranges from experimental 500L/H to industrial 90T/H, with a total of more than 100 standard models. China Ting's organization works closely with customers to help them stay ahead of the industry.
Efficient, powerful, and reliable. For more than 50 years, China Ting separators have always played the role of defender in the field of centrifugal separation technology. Therefore, it can be said that China Ting's development process has not only brought about its responsibility to customers, but also created the company's vision.
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Pharmaceutical Industry Decanter Centrifuge Industry knowledge

How does the Pharmaceutical Industry Decanter Centrifuge ensure separation accuracy and process adaptability?

In the pharmaceutical industry, separation accuracy and process adaptability are crucial, especially in processes such as alcohol precipitation of traditional Chinese medicines and fermentation broths. The equipment utilizes pharmaceutical-grade materials such as 316L stainless steel or titanium alloy, which comply with GMP standards, to effectively prevent metal ion contamination and ensure drug purity.

With a high separation factor of 3136-3567 G, the equipment can accurately separate micron-sized particles, making it particularly suitable for processing suspended solids in traditional Chinese medicine extracts. Furthermore, the equipment's adjustable frequency control system and differential speed control enable it to flexibly handle liquid drugs of varying viscosities, such as concentrated solutions, and achieve excellent results even with high-viscosity drugs.

In the alcohol precipitation process of traditional Chinese medicines, the Pharmaceutical Industry Decanter Centrifuge uses three-phase separation to efficiently separate alcohol, drug solution, and drug residue, maximizing drug recovery while preserving the active ingredients. Its differential speed control system and real-time adjustment of the liquid ring thickness ensure precision and stability during the process, meeting the pharmaceutical industry's high demands for separation accuracy.

How does the Pharmaceutical Industry Decanter Centrifuge ensure process safety and hygienic standards during production?

In the pharmaceutical industry, especially when working with organic solvents, equipment safety is crucial. The Pharmaceutical Industry Decanter Centrifuge features an explosion-proof design, especially when handling organic solvents like alcohol precipitation. Its ATEX-certified motor and fully enclosed structure effectively eliminate the risk of solvent volatilization and explosion, making it safer for use in flammable and explosive environments.

The equipment's interior surface undergoes a fine, hygienic polishing treatment with a surface roughness of Ra ≤ 0.4μm, minimizing drug residue and ensuring that CIP and SIP requirements are met after each use. This fully ensures the high purity and safety of drugs, providing reliable process support for pharmaceutical production.

The equipment's comprehensive cleaning system, equipped with high-pressure nozzles and multi-channel CIP piping, effectively removes accumulated material residues within the screw conveyor system, improving cleaning efficiency and reducing the risk of residual drug contamination. Compared to traditional cleaning methods, the Pharmaceutical Industry Decanter Centrifuge improves cleaning efficiency by over 60%, effectively reducing cross-contamination and improving production hygiene standards.

How does the Pharmaceutical Industry Decanter Centrifuge improve resource utilization and reduce costs?

The Pharmaceutical Industry Decanter Centrifuge not only improves separation accuracy but also significantly enhances resource utilization and reduces material waste during production. During the alcohol precipitation process of traditional Chinese medicine, the Pharmaceutical Industry Decanter Centrifuge efficiently separates alcohol, liquid medicine, and drug residue, ensuring an ethanol recovery rate exceeding 95%, significantly reducing ethanol consumption and production costs. For example, a traditional Chinese medicine injection manufacturer, using the LW450B centrifuge, not only improved separation efficiency but also saved 1.2 million yuan in ethanol costs.

The equipment also offers excellent solid residue dehydration, reducing the moisture content of drug residue to below 50%. This significantly reduces processing costs for subsequent treatment (such as incineration or composting) and improves resource reuse. The Pharmaceutical Industry Decanter Centrifuge utilizes high-torque planetary gears and precisely controlled differential speed control, enabling consistently efficient solids discharge. This reduces the maintenance and cleaning time associated with traditional filters and filter presses, improving overall equipment efficiency.

Pharmaceutical Industry Decanter Centrifuge Maintenance and Operation Recommendations

To ensure the long-term, stable operation of the Pharmaceutical Industry Decanter Centrifuge, regular inspection and maintenance are crucial. The following are some common maintenance recommendations:

Spiral Blade Inspection: To ensure efficient operation of the Pharmaceutical Industry Decanter Centrifuge, inspect the spiral blades for wear every 500 hours. Spiral blades may wear over extended periods of operation, affecting separation performance. If significant wear is observed, dynamic balancing is required to ensure blade stability and accuracy, avoid uneven rotation, and ensure a smooth separation process.

Cleaning Method: To ensure internal cleanliness and prevent cross-contamination, regular cleaning with purified water and a 1% nitric acid solution is recommended. This cleaning method effectively removes drug residue and impurities while ensuring no residual cleaning agents can contaminate drug quality. Thorough cleaning after each production cycle helps extend equipment life and maintains hygiene standards, especially in the stringent pharmaceutical production environment.

Level Baffle Adjustment: The level baffle is a critical adjustment component in the Pharmaceutical Industry Decanter Centrifuge, directly impacting separation performance. Regular inspection and adjustment of the level baffle position is crucial to maintaining efficient equipment operation. Adjusting the level baffle helps optimize liquid stratification and ensure precise separation of solid, liquid, and oil layers, thereby improving separation performance and production efficiency.

Seal Inspection: Equipment seals are crucial for preventing drug spillage and cross-contamination. Screw conveyor system seals require regular inspection and replacement to prevent wear and aging that can lead to leaks and compromise equipment efficiency. Food-grade silicone or PTFE seals are recommended, as these materials meet pharmaceutical industry hygiene standards, effectively preventing cross-contamination and ensuring the safety and quality of drug production.